Carbimazole-induced Anaphylactic Shock: A Case Report

Carbimazole is an antithyroid drug that rarely presents as anaphylactic shock. We hereby report a case of 40-year-old female who was treated with carbimazole for thyrotoxicosis. Patient developed sweating, shortness of breath and altered sensorium after taking single dose of carbimazole. Patient was treated for anaphylactic shock. From this, we want to emphasize that carbimazole can rarely present as anaphylactic shock without any other allergic manifestation. So, patient should be counselled about this rare side effect and early approach to health care facility. KEY MESSAGES: Patient on carbimazole should be aware of all side effects including rare side effects like anaphylactic shock. Studies are required to identify risk factors and new drugs for carbimazole allergy patients. Patient with thyrotoxicosis should also be screened for autoimmune thyrotoxicosis. HOW TO CITE THIS ARTICLE: Keyal NK, Thapa S, Yadav MK. Carbimazole-induced Anaphylactic Shock: A Case Report. Indian J Crit Care Med 2019;23(8):380–381.