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Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones
Atonal homolog 8 (Atoh8) is a transcription factor of the basic helix-loop-helix (bHLH) protein family, which is expressed in the cartilaginous elements of endochondral bones. To analyze its function during chondrogenesis we deleted Atoh8 in mice using a chondrocyte- (Atoh8(flox/flox);Col2a1-Cre) an...
Autores principales: | Schroeder, Nadine, Wuelling, Manuela, Hoffmann, Daniel, Brand-Saberi, Beate, Vortkamp, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709907/ https://www.ncbi.nlm.nih.gov/pubmed/31449527 http://dx.doi.org/10.1371/journal.pone.0218230 |
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