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Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones

Atonal homolog 8 (Atoh8) is a transcription factor of the basic helix-loop-helix (bHLH) protein family, which is expressed in the cartilaginous elements of endochondral bones. To analyze its function during chondrogenesis we deleted Atoh8 in mice using a chondrocyte- (Atoh8(flox/flox);Col2a1-Cre) an...

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Detalles Bibliográficos
Autores principales: Schroeder, Nadine, Wuelling, Manuela, Hoffmann, Daniel, Brand-Saberi, Beate, Vortkamp, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709907/
https://www.ncbi.nlm.nih.gov/pubmed/31449527
http://dx.doi.org/10.1371/journal.pone.0218230

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