Cargando…

Progression of scarring trachoma in Tanzanian children: A four-year cohort study

BACKGROUND: Trachoma is a progressive blinding disease initiated by infection of the conjunctiva with Chlamydia trachomatis. Repeated infections are thought to cause chronic inflammation, which drives scarring, leading to in-turning of the eyelids. The relationship between C. trachomatis, clinical i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramadhani, Athumani M., Derrick, Tamsyn, Macleod, David, Massae, Patrick, Mafuru, Elias, Malisa, Aiweda, Mbuya, Kelvin, Roberts, Chrissy h., Makupa, William, Mtuy, Tara, Bailey, Robin L., Mabey, David C. W., Holland, Martin J., Burton, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709924/ https://www.ncbi.nlm.nih.gov/pubmed/31412025 http://dx.doi.org/10.1371/journal.pntd.0007638

Ejemplares similares

Immunopathogenesis of Progressive Scarring Trachoma: Results of a 4-Year Longitudinal Study in Tanzanian Children
por: Derrick, Tamsyn, et al.
Publicado: (2020)

Ocular immune responses, Chlamydia trachomatis infection and clinical signs of trachoma before and after azithromycin mass drug administration in a treatment naïve trachoma-endemic Tanzanian community
por: Ramadhani, Athumani M., et al.
Publicado: (2019)

The conjunctival microbiome before and after azithromycin mass drug administration for trachoma control in a cohort of Tanzanian children
por: Pickering, Harry, et al.
Publicado: (2022)

Immunofibrogenic Gene Expression Patterns in Tanzanian Children with Ocular Chlamydia trachomatis Infection, Active Trachoma and Scarring: Baseline Results of a 4-Year Longitudinal Study
por: Ramadhani, Athumani M., et al.
Publicado: (2017)

DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas
por: Derrick, Tamsyn R., et al.
Publicado: (2020)

Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells
por: Hu, Victor H., et al.
Publicado: (2016)

Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data
por: Goncalves, Adriana, et al.
Publicado: (2016)

Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease
por: Barton, Amber, et al.
Publicado: (2023)

The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment
por: Ramadhani, Athumani M., et al.
Publicado: (2016)

In Vivo Confocal Microscopy in Scarring Trachoma
por: Hu, Victor H., et al.
Publicado: (2011)

Blinding Trachoma: Systematic Review of Rates and Risk Factors for Progressive Disease
por: Ramadhani, Athumani M., et al.
Publicado: (2016)

Reduced-cost Chlamydia trachomatis-specific multiplex real-time PCR diagnostic assay evaluated for ocular swabs and use by trachoma research programmes
por: Butcher, Robert, et al.
Publicado: (2017)

Pathogenesis of Progressive Scarring Trachoma in Ethiopia and Tanzania and Its Implications for Disease Control: Two Cohort Studies
por: Burton, Matthew J., et al.
Publicado: (2015)

Non-Chlamydial Bacterial Infection and Progression of Conjunctival Scarring in Trachoma
por: Hu, Victor H., et al.
Publicado: (2018)

miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease
por: Derrick, Tamsyn, et al.
Publicado: (2017)

Eyescores: an open platform for secure electronic data and photographic evidence collection in ophthalmological field studies
por: Roberts, Chrissy h, et al.
Publicado: (2013)

Trachoma and Ocular Chlamydial Infection in the Era of Genomics
por: Derrick, Tamsyn, et al.
Publicado: (2015)

Conjunctival MicroRNA Expression in Inflammatory Trachomatous Scarring
por: Derrick, Tamsyn, et al.
Publicado: (2013)

Conjunctival Microbiome-Host Responses Are Associated With Impaired Epithelial Cell Health in Both Early and Late Stages of Trachoma
por: Pickering, Harry, et al.
Publicado: (2019)

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration
por: Martin, Diana L., et al.
Publicado: (2015)

Conjunctival Scarring in Trachoma Is Associated with the HLA-C Ligand of KIR and Is Exacerbated by Heterozygosity at KIR2DL2/KIR2DL3
por: Roberts, Chrissy h., et al.
Publicado: (2014)

In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison
por: Hu, Victor H, et al.
Publicado: (2013)

In Vivo Confocal Microscopy of Trachoma in Relation to Normal Tarsal Conjunctiva
por: Hu, Victor H., et al.
Publicado: (2011)

The Global Burden of Trachoma: A Review
por: Burton, Matthew J., et al.
Publicado: (2009)

Community seroprevalence survey for yaws and trachoma in the Western Division of Fiji
por: Cocks, Naomi, et al.
Publicado: (2016)

Ocular Chlamydia trachomatis infection, anti-Pgp3 antibodies and conjunctival scarring in Vanuatu and Tarawa, Kiribati before antibiotic treatment for trachoma
por: Butcher, Robert, et al.
Publicado: (2020)

Knowledge, perceptions and experiences of trachoma among Maasai in Tanzania: Implications for prevention and control
por: Mtuy, Tara B., et al.
Publicado: (2019)

The utility of serology for elimination surveillance of trachoma
por: Pinsent, Amy, et al.
Publicado: (2018)

Empowering Maasai women behind the camera: Photovoice as a tool for trachoma control
por: Mtuy, Tara B., et al.
Publicado: (2021)

Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with Chlamydia trachomatis
por: Butcher, Robert, et al.
Publicado: (2018)

Conjunctival Scarring, Corneal Pannus, and Herbert’s Pits in Adolescent Children in Trachoma-endemic Populations of the Solomon Islands and Vanuatu
por: Butcher, Robert, et al.
Publicado: (2020)

The Distribution of Ocular Chlamydia Prevalence across Tanzanian Communities Where Trachoma Is Declining
por: Rahman, Salman A., et al.
Publicado: (2015)

Chlamydia trachomatis ompA Variants in Trachoma: What Do They Tell Us?
por: Andreasen, Aura A., et al.
Publicado: (2008)

Epidemiology and control of trachoma: systematic review
por: Hu, Victor H, et al.
Publicado: (2010)

Active Trachoma and Ocular Chlamydia trachomatis Infection in Two Gambian Regions: On Course for Elimination by 2020?
por: Harding-Esch, Emma M., et al.
Publicado: (2009)

Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study
por: Last, Anna, et al.
Publicado: (2017)

Low Prevalence of Ocular Chlamydia trachomatis Infection and Active Trachoma in the Western Division of Fiji
por: Macleod, Colin K., et al.
Publicado: (2016)

Correction: The Distribution of Ocular Chlamydia Prevalence across Tanzanian Communities Where Trachoma Is Declining
por: Rahman, Salman A., et al.
Publicado: (2015)

Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies
por: Migchelsen, Stephanie J., et al.
Publicado: (2017)

Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye
por: Butcher, Robert M. R., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ojkld7mev492f4j4fao0b0sn0t