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Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury
The antioxidant function of Klotho is well-documented as a regulatory factor implicated in countering the aging process. This study investigated whether ginseng upregulates Klotho and its antiaging signaling in a setting of calcineurin inhibitor-induced oxidative stress. Although tacrolimus treatmen...
Autores principales: | Lim, Sun Woo, Shin, Yoo Jin, Luo, Kang, Quan, Yi, Cui, Sheng, Ko, Eun Jeong, Chung, Byung Ha, Yang, Chul Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710054/ https://www.ncbi.nlm.nih.gov/pubmed/31400753 http://dx.doi.org/10.18632/aging.102137 |
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