Establishment and characterization of a fucosylated α-fetoprotein-specific monoclonal antibody: a potential application for clinical research

The Lens culinaris agglutinin (LCA)-reactive fraction of α-fetoprotein (AFP-L3) is a well-known cancer biomarker for hepatocellular carcinoma (HCC) with very high specificity. Because LCA recognizes only bi-antennary N-glycans with a core fucose, some of fucosylated AFP in HCC patients may not be de...

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Detalles Bibliográficos
Autores principales: Egashira, Yuriko, Suganuma, Masatoshi, Kataoka, Yukiko, Higa, Yukiko, Ide, Nobuyuki, Morishita, Koichi, Kamada, Yoshihiro, Gu, Jianguo, Fukagawa, Koji, Miyoshi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710264/
https://www.ncbi.nlm.nih.gov/pubmed/31451706
http://dx.doi.org/10.1038/s41598-019-48821-x

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