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A conserved regulatory program initiates lateral plate mesoderm emergence across chordates

Cardiovascular lineages develop together with kidney, smooth muscle, and limb connective tissue progenitors from the lateral plate mesoderm (LPM). How the LPM initially emerges and how its downstream fates are molecularly interconnected remain unknown. Here, we isolate a pan-LPM enhancer in the zebr...

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Detalles Bibliográficos
Autores principales: Prummel, Karin D., Hess, Christopher, Nieuwenhuize, Susan, Parker, Hugo J., Rogers, Katherine W., Kozmikova, Iryna, Racioppi, Claudia, Brombacher, Eline C., Czarkwiani, Anna, Knapp, Dunja, Burger, Sibylle, Chiavacci, Elena, Shah, Gopi, Burger, Alexa, Huisken, Jan, Yun, Maximina H., Christiaen, Lionel, Kozmik, Zbynek, Müller, Patrick, Bronner, Marianne, Krumlauf, Robb, Mosimann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710290/
https://www.ncbi.nlm.nih.gov/pubmed/31451684
http://dx.doi.org/10.1038/s41467-019-11561-7