Cargando…

Potential Therapeutic Effects of Exosomes Packed With a miR-21-Sponge Construct in a Rat Model of Glioblastoma

Glioblastoma multiforme (GBM) is a grade 4 and the most aggressive form of glioma, with a poor response to current treatments. The expression of microRNAs (miRNAs) is widely dysregulated in various cancers, including GBM. One of the overexpressed miRNAs in GBM is miR-21 which promotes proliferation,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monfared, Hamideh, Jahangard, Yavar, Nikkhah, Maryam, Mirnajafi-Zadeh, Javad, Mowla, Seyed Javad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710330/ https://www.ncbi.nlm.nih.gov/pubmed/31482067 http://dx.doi.org/10.3389/fonc.2019.00782

Ejemplares similares

Therapeutic Effects of Transplanted Exosomes Containing miR-29b to a Rat Model of Alzheimer’s Disease
por: Jahangard, Yavar, et al.
Publicado: (2020)

Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
por: Bayat, Hadi, et al.
Publicado: (2023)

Up-regulation of miR-21 decreases chemotherapeutic effect of dendrosomal curcumin in breast cancer cells
por: Esmatabadi, Mohammad Javad Dehghan, et al.
Publicado: (2017)

Straightforward and Cost-Effective Production of RADA-16I Peptide in Escherichia coli
por: Fouani, Mohamad Hassan, et al.
Publicado: (2019)

Radiosensitization of breast cancer cells using AS1411 aptamer-conjugated gold nanoparticles
por: Mehrnia, Somayeh Sadat, et al.
Publicado: (2021)

Differential miRNAs expression pattern of irradiated breast cancer cell lines is correlated with radiation sensitivity
por: Masoudi-Khoram, Nastaran, et al.
Publicado: (2020)

Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells
por: Tahmasebi Mirgani, Maryam, et al.
Publicado: (2014)

Fibroblast Growth Factor-2 Enhanced The Recruitment of Progenitor Cells and Myelin Repair in Experimental Demyelination of Rat Hippocampal Formations
por: Azin, Mahdieh, et al.
Publicado: (2015)

Low-frequency Stimulation Decreases Hyperexcitability Through Adenosine A1 Receptors in the Hippocampus of Kindled Rats
por: Shojaee, Amir, et al.
Publicado: (2020)

Engrafted Human Induced Pluripotent Stem Cell-Derived Anterior Specified Neural Progenitors Protect the Rat Crushed Optic Nerve
por: Satarian, Leila, et al.
Publicado: (2013)

Comparing the synaptic potentiation in schaffer collateral-CA1 synapses in dorsal and intermediate regions of the hippocampus in normal and kindled rats
por: Sharifi, Maryam, et al.
Publicado: (2023)

Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators
por: Malakootian, Mahshid, et al.
Publicado: (2022)

Expression, Tissue Distribution and Function of miR-21 in Esophageal Squamous Cell Carcinoma
por: Nouraee, Nazila, et al.
Publicado: (2013)

miR-4284 and miR-4484 as Putative Biomarkers for Diffuse Large B-Cell Lymphoma
por: Tamaddon, Gholamhossein, et al.
Publicado: (2016)

Parvalbumin-expressing interneurons can act solo while somatostatin-expressing interneurons act in chorus in most cases on cortical pyramidal cells
por: Safari, Mir-Shahram, et al.
Publicado: (2017)

Aberrant Expression of Breast Development-Related MicroRNAs, miR-22, miR-132, and miR-212, in Breast Tumor Tissues
por: Damavandi, Zahra, et al.
Publicado: (2016)

Effects of Low Frequency Stimulation on Spontaneous Inhibitory and Excitatory Post-Synaptic Currents in Hippocampal CA1 Pyramidal Cells of Kindled Rats
por: Ghafouri, Samireh, et al.
Publicado: (2017)

Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test
por: Esmaeilpour, Khadijeh, et al.
Publicado: (2018)

Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
por: Fatemeh, Bakhtiarzadeh, et al.
Publicado: (2023)

Upregulation of Pluripotency Markers in Adipose Tissue-Derived Stem Cells by miR-302 and Leukemia Inhibitory Factor
por: Taha, Masoumeh Fakhr, et al.
Publicado: (2014)

In Vitro Differentiation of Neural Stem Cells into Noradrenergic-Like Cells
por: Pirhajati Mahabadi, Vahid, et al.
Publicado: (2015)

MiR-21 Expression in Wilms’ Tumor
por: Bazzaz, Navid, et al.
Publicado: (2018)

Study of Sedative-Hypnotic Effects of Aloe vera L. Aqueous Extract through Behavioral Evaluations and EEG Recording in Rats
por: Abdollahnejad, Fatemeh, et al.
Publicado: (2016)

Down-regulation of miR-302b, an ESC-specific microRNA, in Gastric Adenocarcinoma
por: Khalili, Mitra, et al.
Publicado: (2012)

Down-Regulatory Effects of miR-211 on Long Non-Coding RNA SOX2OT and SOX2 Genes in Esophageal Squamous Cell Carcinoma
por: Shafiee, Mohammad, et al.
Publicado: (2016)

Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer
por: Yazarlou, Fatemeh, et al.
Publicado: (2018)

Comparing the Anticonvulsant Effects of Low Frequency Stimulation of Different Brain Sites on the Amygdala Kindling Acquisition in Rats
por: Esmaeilpour, Khadijeh, et al.
Publicado: (2013)

Low Frequency Electrical Stimulation Attenuated The Epileptiform Activity-Induced Changes in Action Potential Features in Hippocampal CA1 Pyramidal Neurons
por: Ghasemi, Zahra, et al.
Publicado: (2018)

Low-Frequency Stimulation Prevents Kindling-Induced Impairment through the Activation of the Endocannabinoid System
por: Khajei, Sina, et al.
Publicado: (2021)

Effect of Deep Brain Stimulation in The Ventral Tegmental Area on Neuronal Activity in Local and Remote Brain Regions in Kindled Mice
por: Esmaeili Tazangi, Parisa, et al.
Publicado: (2023)

Expression of the miR-302/367 microRNA cluster is regulated by a conserved long non-coding host-gene
por: Rahimi, Karim, et al.
Publicado: (2021)

MiR-9-5p and miR-106a-5p dysregulated in CD4(+) T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation
por: Majd, Maryam, et al.
Publicado: (2018)

Spatial Learning and Memory in Barnes Maze Test and Synaptic Potentiation in Schaffer Collateral-CA1 Synapses of Dorsal Hippocampus in Freely Moving Rats
por: Sadeghian, Azam, et al.
Publicado: (2019)

miR-361-5p as a promising qRT-PCR internal control for tumor and normal breast tissues
por: Ghanbari, Sogol, et al.
Publicado: (2021)

Disrupted connectivity in the olfactory bulb-entorhinal cortex-dorsal hippocampus circuit is associated with recognition memory deficit in Alzheimer’s disease model
por: Salimi, Morteza, et al.
Publicado: (2022)

Up-regulation of CatSper genes family by selenium
por: Mohammadi, Shabnam, et al.
Publicado: (2009)

Spermatogonial Stem Cell Transplantation and Subsequent Orchidopexy in the Bilateral Cryptorchid Mouse Model
por: Absalan, Forouzan, et al.
Publicado: (2011)

Vitrification of Mouse MII Oocyte Decreases the Mitochondrial DNA Copy Number, TFAM Gene Expression and Mitochondrial Enzyme Activity
por: Amoushahi, Mahboobeh, et al.
Publicado: (2017)

Enrichment of A Rare Subpopulation of miR-302-Expressing Glioma Cells by Serum Deprivation
por: Rafiee, Mahmoud-Reza, et al.
Publicado: (2015)

Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats
por: Ghafouri, Samireh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ufsa9tt48hn2cnh3eao6stpkkd