Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first step in the kynurenine pathway of tryptophan (Trp) degradation that produces several biologically active Trp metabolites. L-kynurenine (Kyn), the first byproduct by IDO1, promotes immunoregulatory effects via activation of the Aryl hydrocarbon...

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Detalles Bibliográficos
Autores principales: Gargaro, Marco, Vacca, Carmine, Massari, Serena, Scalisi, Giulia, Manni, Giorgia, Mondanelli, Giada, Mazza, Emilia M. C., Bicciato, Silvio, Pallotta, Maria T., Orabona, Ciriana, Belladonna, Maria L., Volpi, Claudia, Bianchi, Roberta, Matino, Davide, Iacono, Alberta, Panfili, Eleonora, Proietti, Elisa, Iamandii, Ioana Maria, Cecchetti, Violetta, Puccetti, Paolo, Tabarrini, Oriana, Fallarino, Francesca, Grohmann, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710348/
https://www.ncbi.nlm.nih.gov/pubmed/31481962
http://dx.doi.org/10.3389/fimmu.2019.01973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710348/
https://www.ncbi.nlm.nih.gov/pubmed/31481962
http://dx.doi.org/10.3389/fimmu.2019.01973

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