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Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux via Up-regulation of SIRT1

Hyperglycemia, a key characteristic and risk factor for diabetes mellitus (DM), causes neuronal senescence. Hydrogen sulfide (H(2)S) is a novel neuroprotectant. The present work was to investigate the potential effect of H(2)S on hyperglycemia-induced neuronal senescence and the underlying mechanism...

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Detalles Bibliográficos
Autores principales:	Wu, Lei, Chen, Ying, Wang, Chun-Yan, Tang, Yi-Yun, Huang, Hong-Lin, Kang, Xuan, Li, Xiang, Xie, Yu-Rong, Tang, Xiao-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442/ https://www.ncbi.nlm.nih.gov/pubmed/31481873 http://dx.doi.org/10.3389/fnmol.2019.00194

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