Pharmacokinetics and safety of tobramycin nebulization with the I‐neb and PARI‐LC Plus in children with cystic fibrosis: A randomized, crossover study

AIMS: We aimed to compare the pharmacokinetics (PK) and safety profile of tobramycin inhalation solution (TIS) using the I‐neb device to the standard PARI‐LC Plus nebulizer in children with cystic fibrosis. METHODS: A randomized, open‐label, crossover study was performed. In 2 separate study visits,...

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Detalles Bibliográficos
Autores principales: van Velzen, Annelies J., Uges, Joris W.F., Heijerman, Harry G.M., Arets, Bert G.M., Nuijsink, Marianne, van der Wiel‐Kooij, Els C., van Maarseveen, Erik M., van Zanten, Gijsbert A., Pullens, Bas, Touw, Daan J., Janssens, Hettie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710527/
https://www.ncbi.nlm.nih.gov/pubmed/31112621
http://dx.doi.org/10.1111/bcp.13988

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