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Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs

The generation of humanized ectopic ossicles (hOss) in mice has been proposed as an advanced translational and fundamental model to study the human hematopoietic system. The approach relies on the presence of human bone marrow-derived mesenchymal stromal cells (hMSCs) supporting the engraftment of t...

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Detalles Bibliográficos
Autores principales: Bourgine, Paul E., Fritsch, Kristin, Pigeot, Sebastien, Takizawa, Hitoshi, Kunz, Leo, Kokkaliaris, Konstantinos D., Coutu, Daniel L., Manz, Markus G., Martin, Ivan, Schroeder, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710718/
https://www.ncbi.nlm.nih.gov/pubmed/31442666
http://dx.doi.org/10.1016/j.isci.2019.08.006