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ULK1/2 Restricts the Formation of Inducible SINT-Speckles, Membraneless Organelles Controlling the Threshold of TBK1 Activation

Membraneless organelles (MLOs) are liquid-like subcellular compartments providing spatiotemporal control to biological processes. This study reveals that cellular stress leads to the incorporation of the adaptor protein SINTBAD (TBKBP1) into membraneless, cytosolic speckles. Determination of the int...

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Detalles Bibliográficos
Autores principales:	Saul, Vera Vivian, Seibert, Markus, Krüger, Marcus, Jeratsch, Sylvia, Kracht, Michael, Schmitz, Michael Lienhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710720/ https://www.ncbi.nlm.nih.gov/pubmed/31442668 http://dx.doi.org/10.1016/j.isci.2019.08.001

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