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Association of ESR1 Mutations and Visceral Metastasis in Patients with Estrogen Receptor-Positive Advanced Breast Cancer from Brazil

Mutations in the ESR1 gene (ESR1m) are important mechanisms of resistance to endocrine therapy in estrogen receptor-positive advanced breast cancer and have been recognized as a prognostic and predictive biomarker as well as a potential therapeutic target. However, the prevalence of ESR1m in real-wo...

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Detalles Bibliográficos
Autores principales: Reinert, Tomás, Coelho, Guilherme Portela, Mandelli, Jovana, Zimermann, Edinéia, Zaffaroni, Facundo, Bines, José, Barrios, Carlos Henrique, Graudenz, Marcia Silveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710809/
https://www.ncbi.nlm.nih.gov/pubmed/31511774
http://dx.doi.org/10.1155/2019/1947215