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Association of ESR1 Mutations and Visceral Metastasis in Patients with Estrogen Receptor-Positive Advanced Breast Cancer from Brazil
Mutations in the ESR1 gene (ESR1m) are important mechanisms of resistance to endocrine therapy in estrogen receptor-positive advanced breast cancer and have been recognized as a prognostic and predictive biomarker as well as a potential therapeutic target. However, the prevalence of ESR1m in real-wo...
Autores principales: | Reinert, Tomás, Coelho, Guilherme Portela, Mandelli, Jovana, Zimermann, Edinéia, Zaffaroni, Facundo, Bines, José, Barrios, Carlos Henrique, Graudenz, Marcia Silveira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710809/ https://www.ncbi.nlm.nih.gov/pubmed/31511774 http://dx.doi.org/10.1155/2019/1947215 |
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