Cargando…

Cancer Panel Assay for Precision Oncology Clinic: Results from a 1-Year Study

Next-generation sequencing (NGS)-based cancer panel tests are actively being applied in the clinic for precision oncology. Given the importance of NGS panel tests in the palliative clinical setting, it is critical to understand success rates, factors responsible for test failures, and the incidence...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Dohee, Kim, Binnari, Shin, Hyeong Chan, Kim, Eun Ji, Ha, Sang Yun, Jang, Kee-Taek, Kim, Seung Tae, Lee, Jeeyun, Kang, Won Ki, Park, Joon Oh, Kim, Kyoung-Mee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710823/ https://www.ncbi.nlm.nih.gov/pubmed/31442744 http://dx.doi.org/10.1016/j.tranon.2019.07.017

Ejemplares similares

DNA-protein biomarkers for immunotherapy in the era of precision oncology
por: Kim, Binnari, et al.
Publicado: (2021)

Tumor Mutational Burden Determined by Panel Sequencing Predicts Survival After Immunotherapy in Patients With Advanced Gastric Cancer
por: Kim, Jinchul, et al.
Publicado: (2020)

Role of Exosomes and Their Potential as Biomarkers in Epstein-Barr Virus-Associated Gastric Cancer
por: Kim, Binnari, et al.
Publicado: (2023)

To Excavate Biomarkers Predictive of the Response for Capecitabine plus RAD001 through Nanostring-Based Multigene Assay in Advanced Gastric Cancer Patients
por: Lee, Hansang, et al.
Publicado: (2016)

RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis
por: Kim, Hee Kyung, et al.
Publicado: (2019)

Detection of Fusion Genes Using a Targeted RNA Sequencing Panel in Gastrointestinal and Rare Cancers
por: Lee, Su Jin, et al.
Publicado: (2020)

Prospective blinded study of somatic mutation detection in cell-free DNA utilizing a targeted 54-gene next generation sequencing panel in metastatic solid tumor patients
por: Kim, Seung Tae, et al.
Publicado: (2015)

GSTT1 Copy Number Gain and ZNF Overexpression Are Predictors of Poor Response to Imatinib in Gastrointestinal Stromal Tumors
por: Lee, Eui Jin, et al.
Publicado: (2013)

Comprehensive molecular and clinical characterization of Asian melanoma patients treated with anti-PD-1 antibody
por: Lee, Jiyun, et al.
Publicado: (2019)

Isolated Mass-Forming IgG4-Related Cholangitis as an Initial Clinical Presentation of Systemic IgG4-Related Disease
por: Kim, Seokhwi, et al.
Publicado: (2016)

Comparison of Three BRAF Mutation Tests in Formalin-Fixed Paraffin Embedded Clinical Samples
por: Ahn, Soomin, et al.
Publicado: (2013)

PTEN Protein Loss and Loss-of-Function Mutations in Gastric Cancers: The Relationship with Microsatellite Instability, EBV, HER2, and PD-L1 Expression
por: Kim, Binnari, et al.
Publicado: (2020)

Development of mesenchymal subtype gene signature for clinical application in gastric cancer
por: Lee, Jeeyun, et al.
Publicado: (2017)

Comprehensive molecular characterization of gastric cancer patients from phase II second-line ramucirumab plus paclitaxel therapy trial
por: Kim, Seung Tae, et al.
Publicado: (2021)

Digital image analysis in pathologist‐selected regions of interest predicts survival more accurately than whole‐slide analysis: a direct comparison study in 153 gastric carcinomas
por: Heo, You Jeong, et al.
Publicado: (2020)

Gastroenteropancreatic Neuroendocrine Tumors with Liver Metastases in Korea: A Clinicopathological Analysis of 72 Cases in a Single Institute
por: Shin, Yooju, et al.
Publicado: (2015)

The Impact of PD-L1 Expression in Patients with Metastatic GEP-NETs
por: Kim, Seung Tae, et al.
Publicado: (2016)

Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer
por: Yi, Jun Ho, et al.
Publicado: (2014)

Tumour shrinkage at 6 weeks predicts favorable clinical outcomes in a phase III study of gemcitabine and oxaliplatin with or without erlotinib for advanced biliary tract cancer
por: Kim, Seung Tae, et al.
Publicado: (2015)

Correlating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy
por: Kim, Seung Tae, et al.
Publicado: (2017)

Clinical sequencing to assess tumor mutational burden as a useful biomarker to immunotherapy in various solid tumors
por: Kim, Hana, et al.
Publicado: (2021)

Clinical Circulating Tumor DNA Testing for Precision Oncology
por: Kim, Hyunji, et al.
Publicado: (2023)

Clinicopathologic significance of the delta-like ligand 4, vascular endothelial growth factor, and hypoxia-inducible factor-2α in gallbladder cancer
por: Park, Sujin, et al.
Publicado: (2023)

The Impact of Concomitant Genomic Alterations on Treatment Outcome for Trastuzumab Therapy in HER2-Positive Gastric Cancer
por: Lee, Ji Yun, et al.
Publicado: (2015)

Impact of programmed death‐ligand 1 (PD‐L1) positivity on clinical and molecular features of patients with metastatic gastric cancer
por: Shin, Minkyue, et al.
Publicado: (2023)

Molecular Subgroup Analysis of Clinical Outcomes in a Phase 3 Study of Gemcitabine and Oxaliplatin with or without Erlotinib in Advanced Biliary Tract Cancer
por: Kim, Seung Tae, et al.
Publicado: (2015)

PIK3CA mutation detection in metastatic biliary cancer using cell-free DNA
por: Kim, Seung Tae, et al.
Publicado: (2015)

Claudin 18.2 expression in various tumor types and its role as a potential target in advanced gastric cancer
por: Hong, Jung Yong, et al.
Publicado: (2020)

Deep learning-based virtual cytokeratin staining of gastric carcinomas to measure tumor–stroma ratio
por: Hong, Yiyu, et al.
Publicado: (2021)

Antitumor Effect of AZD4547 in a Fibroblast Growth Factor Receptor 2–Amplified Gastric Cancer Patient–Derived Cell Model()
por: Jang, Jiryeon, et al.
Publicado: (2017)

The prevalence of homologous recombination deficiency (HRD) in various solid tumors and the role of HRD as a single biomarker to immune checkpoint inhibitors
por: Kim, Hana, et al.
Publicado: (2021)

The Clinical Impact of c-MET Over-Expression in Advanced Biliary Tract Cancer (BTC)
por: Heo, Mi Hwa, et al.
Publicado: (2017)

Direct comparison of the next-generation sequencing and iTERT PCR methods for the diagnosis of TERT hotspot mutations in advanced solid cancers
por: Kang, So Young, et al.
Publicado: (2022)

Dysregulated miRNA in a cancer-prone environment: A study of gastric non-neoplastic mucosa
por: Kim, Binnari, et al.
Publicado: (2020)

Comprehensive immunoprofile analysis of prognostic markers in pancreaticobiliary tract cancers
por: Kim, Ji Eun, et al.
Publicado: (2023)

NCOA4-RET fusion in colorectal cancer: Therapeutic challenge using patient-derived tumor cell lines
por: Kim, Sun Young, et al.
Publicado: (2018)

Prognostic Impact of Sarcopenia and Radiotherapy in Patients With Advanced Gastric Cancer Treated With Anti-PD-1 Antibody
por: Kim, Nalee, et al.
Publicado: (2021)

Current challenges in the implementation of precision oncology for the management of metastatic colorectal cancer
por: Kim, Sun Young, et al.
Publicado: (2020)

MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines
por: Kim, Jung Eun, et al.
Publicado: (2017)

Four distinct immune microenvironment subtypes in gastric adenocarcinoma with special reference to microsatellite instability
por: Cho, Junhun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_u2s48rgg6hrd0qcf95datm07qp