If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”

The existence of polymyalgia rheumatica (PMR) induced by statins has been hypothesised by some investigators. This review article highlights the fact that there is no evidence it is real. On the contrary, PMR and statin-associated muscle symptoms (SAMS) are two totally different conditions. Shoulder...

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Detalles Bibliográficos
Autor principal: Manzo, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2019
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710838/
https://www.ncbi.nlm.nih.gov/pubmed/31462832
http://dx.doi.org/10.5114/reum.2019.86427
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author Manzo, Ciro
author_facet Manzo, Ciro
author_sort Manzo, Ciro
collection PubMed
description The existence of polymyalgia rheumatica (PMR) induced by statins has been hypothesised by some investigators. This review article highlights the fact that there is no evidence it is real. On the contrary, PMR and statin-associated muscle symptoms (SAMS) are two totally different conditions. Shoulder and hip ultrasound (US) examinations can make an important contribution in distinguishing a true case of PMR from a PMR-like illness induced by statins. The possibility that SAMS may worsen the clinical manifestations of a PMR patient should be taken into account in clinical practice, and drug discontinuation should be proposed when deterioration or relapse is not otherwise justifiable.
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spelling pubmed-67108382019-08-28 If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica” Manzo, Ciro Reumatologia Review Paper The existence of polymyalgia rheumatica (PMR) induced by statins has been hypothesised by some investigators. This review article highlights the fact that there is no evidence it is real. On the contrary, PMR and statin-associated muscle symptoms (SAMS) are two totally different conditions. Shoulder and hip ultrasound (US) examinations can make an important contribution in distinguishing a true case of PMR from a PMR-like illness induced by statins. The possibility that SAMS may worsen the clinical manifestations of a PMR patient should be taken into account in clinical practice, and drug discontinuation should be proposed when deterioration or relapse is not otherwise justifiable. Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2019-06-28 2019 /pmc/articles/PMC6710838/ /pubmed/31462832 http://dx.doi.org/10.5114/reum.2019.86427 Text en Copyright: © 2019 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Review Paper
Manzo, Ciro
If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title_full If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title_fullStr If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title_full_unstemmed If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title_short If something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
title_sort if something looks like an apple, is it necessarily an apple? – reflections on so-called “statin-induced polymyalgia rheumatica”
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710838/
https://www.ncbi.nlm.nih.gov/pubmed/31462832
http://dx.doi.org/10.5114/reum.2019.86427
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