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Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey
CONTEXT: Asthma patients often suffer from concomitant allergic rhinitis (AR). However, there is paucity of such data from India. AIMS: This questionnaire-based survey evaluated the coexistence of AR in Indian asthmatics, and examined the inter-relationship between the two disease conditions. SUBJEC...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710977/ https://www.ncbi.nlm.nih.gov/pubmed/31464213 http://dx.doi.org/10.4103/lungindia.lungindia_491_18 |
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author | Jaggi, Vikram Dalal, Alpa Ramesh, BR Tikkiwal, Sharad Chaudhry, Anil Kothari, Nisha Lopez, Meena Gogtay, Jaideep |
author_facet | Jaggi, Vikram Dalal, Alpa Ramesh, BR Tikkiwal, Sharad Chaudhry, Anil Kothari, Nisha Lopez, Meena Gogtay, Jaideep |
author_sort | Jaggi, Vikram |
collection | PubMed |
description | CONTEXT: Asthma patients often suffer from concomitant allergic rhinitis (AR). However, there is paucity of such data from India. AIMS: This questionnaire-based survey evaluated the coexistence of AR in Indian asthmatics, and examined the inter-relationship between the two disease conditions. SUBJECTS AND METHODS: This survey conducted in ten cities across India, aimed to generate information on exposure to risk factors, history of atopy, the severity of asthma, and treatment regimen in patients with physician-diagnosed asthma. RESULTS: Data were obtained from 1161 asthma patients (mean age [±standard deviation]: 40.41 [±17.05] years). Prevalence of coexisting AR was found to be 65.24%, with the highest prevalence (80%) in the southern regions of India. Sneezing (71.78%) followed by watery, runny nose (63.59%) were the most common AR symptoms. Majority (72.32%) of the patients had seasonal AR. Coexistence of AR and asthma was significantly associated with the presence of personal and family history of atopy (odds ratio 2.53 and 1.51 respectively; both P < 0.005). Passive smoking, exposure to biomass fuel, and the presence of pets and animals at home were also significantly (P < 0.005) associated with AR-asthma coexistence. Prevalence of AR was found to increase with increasing asthma severity. The usage of oral steroids was significantly higher in patients with coexistent AR-asthma. Sixty-six percent of the patients with coexistent AR-asthma were prescribed intranasal corticosteroids. CONCLUSIONS: The results of the Coexistence of Allergic Rhinitis and ASthma (CARAS) survey highlight the high prevalence of concomitant AR in Indian patients with asthma, and reinforce the need for early diagnosis and guideline-based management of AR in patients with asthma. |
format | Online Article Text |
id | pubmed-6710977 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-67109772019-09-12 Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey Jaggi, Vikram Dalal, Alpa Ramesh, BR Tikkiwal, Sharad Chaudhry, Anil Kothari, Nisha Lopez, Meena Gogtay, Jaideep Lung India Original Article CONTEXT: Asthma patients often suffer from concomitant allergic rhinitis (AR). However, there is paucity of such data from India. AIMS: This questionnaire-based survey evaluated the coexistence of AR in Indian asthmatics, and examined the inter-relationship between the two disease conditions. SUBJECTS AND METHODS: This survey conducted in ten cities across India, aimed to generate information on exposure to risk factors, history of atopy, the severity of asthma, and treatment regimen in patients with physician-diagnosed asthma. RESULTS: Data were obtained from 1161 asthma patients (mean age [±standard deviation]: 40.41 [±17.05] years). Prevalence of coexisting AR was found to be 65.24%, with the highest prevalence (80%) in the southern regions of India. Sneezing (71.78%) followed by watery, runny nose (63.59%) were the most common AR symptoms. Majority (72.32%) of the patients had seasonal AR. Coexistence of AR and asthma was significantly associated with the presence of personal and family history of atopy (odds ratio 2.53 and 1.51 respectively; both P < 0.005). Passive smoking, exposure to biomass fuel, and the presence of pets and animals at home were also significantly (P < 0.005) associated with AR-asthma coexistence. Prevalence of AR was found to increase with increasing asthma severity. The usage of oral steroids was significantly higher in patients with coexistent AR-asthma. Sixty-six percent of the patients with coexistent AR-asthma were prescribed intranasal corticosteroids. CONCLUSIONS: The results of the Coexistence of Allergic Rhinitis and ASthma (CARAS) survey highlight the high prevalence of concomitant AR in Indian patients with asthma, and reinforce the need for early diagnosis and guideline-based management of AR in patients with asthma. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6710977/ /pubmed/31464213 http://dx.doi.org/10.4103/lungindia.lungindia_491_18 Text en Copyright: © 2019 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Jaggi, Vikram Dalal, Alpa Ramesh, BR Tikkiwal, Sharad Chaudhry, Anil Kothari, Nisha Lopez, Meena Gogtay, Jaideep Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title | Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title_full | Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title_fullStr | Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title_full_unstemmed | Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title_short | Coexistence of allergic rhinitis and asthma in Indian patients: The CARAS survey |
title_sort | coexistence of allergic rhinitis and asthma in indian patients: the caras survey |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710977/ https://www.ncbi.nlm.nih.gov/pubmed/31464213 http://dx.doi.org/10.4103/lungindia.lungindia_491_18 |
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