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Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens

BACKGROUND: Multidrug-resistant (MDR) Acinetobacter baumannii infections have high mortality rates and few treatment options. Synergistic drug combinations may improve clinical outcome and reduce further emergence of resistance in MDR pathogens. Here we show an unexpected potent synergy of two trans...

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Detalles Bibliográficos
Autores principales: Dillon, Nicholas, Holland, Michelle, Tsunemoto, Hannah, Hancock, Bryan, Cornax, Ingrid, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711115/
https://www.ncbi.nlm.nih.gov/pubmed/31353294
http://dx.doi.org/10.1016/j.ebiom.2019.07.041