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Paternal bias expression of Igf2as is enhancer-dependent on the imprinting cluster of Igf2, H19 and Nctc1 in muscle cells

Igf2, H19, and Nctc1 are linked co-regulated genes on distal mouse chromosome 7. This locus is an important model both for studying mechanisms of monoallelic expression and for elucidating the role of cis-regulatory elements – enhancers and insulators – in organizing chromatin and gene expression ac...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Young, Youn, Hwa Young, Pfeifer, Karl, Eun, Bokkee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711144/
https://www.ncbi.nlm.nih.gov/pubmed/31489250
http://dx.doi.org/10.1080/19768354.2019.1612780