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Hibernoma: a rare benign soft tissue tumour resembling liposarcoma

Hibernoma is a rare benign soft tissue tumour that can mimic a liposarcoma on radiographic imaging. Our case series review illustrates the clinical presentation and radiographic appearances of four patients with histologically confirmed hibernoma. Hibernoma is usually hypointense relative to subcuta...

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Autores principales: Kovitwanichkanont, Tom, Naidoo, Parm, Guio-Aguilar, Pedro, Leong, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711274/
https://www.ncbi.nlm.nih.gov/pubmed/31489209
http://dx.doi.org/10.1259/bjrcr.20170067
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author Kovitwanichkanont, Tom
Naidoo, Parm
Guio-Aguilar, Pedro
Leong, James
author_facet Kovitwanichkanont, Tom
Naidoo, Parm
Guio-Aguilar, Pedro
Leong, James
author_sort Kovitwanichkanont, Tom
collection PubMed
description Hibernoma is a rare benign soft tissue tumour that can mimic a liposarcoma on radiographic imaging. Our case series review illustrates the clinical presentation and radiographic appearances of four patients with histologically confirmed hibernoma. Hibernoma is usually hypointense relative to subcutaneous fat on T (1) weighted MRI and demonstrates partial fat suppression on fat-saturated sequences. Large intratumoral vessels likely support the diagnosis of hibernoma but are not invariably present. Fludeoxyglucose avidity on PET scan is not beneficial in distinguishing hibernoma from soft tissue malignancy because of its inherent, metabolically active property. Owing to the radiographic heterogeneity of hibernoma, it is currently not possible to diagnose hibernoma based on imaging characteristics alone. Given the excellent prognosis of hibernoma with marginal excision alone, an appreciation of the radiographic features is helpful in the appropriate pre-operative workup of soft tissue tumours.
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spelling pubmed-67112742019-09-05 Hibernoma: a rare benign soft tissue tumour resembling liposarcoma Kovitwanichkanont, Tom Naidoo, Parm Guio-Aguilar, Pedro Leong, James BJR Case Rep Case Review Hibernoma is a rare benign soft tissue tumour that can mimic a liposarcoma on radiographic imaging. Our case series review illustrates the clinical presentation and radiographic appearances of four patients with histologically confirmed hibernoma. Hibernoma is usually hypointense relative to subcutaneous fat on T (1) weighted MRI and demonstrates partial fat suppression on fat-saturated sequences. Large intratumoral vessels likely support the diagnosis of hibernoma but are not invariably present. Fludeoxyglucose avidity on PET scan is not beneficial in distinguishing hibernoma from soft tissue malignancy because of its inherent, metabolically active property. Owing to the radiographic heterogeneity of hibernoma, it is currently not possible to diagnose hibernoma based on imaging characteristics alone. Given the excellent prognosis of hibernoma with marginal excision alone, an appreciation of the radiographic features is helpful in the appropriate pre-operative workup of soft tissue tumours. The British Institute of Radiology. 2018-02-13 /pmc/articles/PMC6711274/ /pubmed/31489209 http://dx.doi.org/10.1259/bjrcr.20170067 Text en © 2018 The Authors. Published by the British Institute of Radiology This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Review
Kovitwanichkanont, Tom
Naidoo, Parm
Guio-Aguilar, Pedro
Leong, James
Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title_full Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title_fullStr Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title_full_unstemmed Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title_short Hibernoma: a rare benign soft tissue tumour resembling liposarcoma
title_sort hibernoma: a rare benign soft tissue tumour resembling liposarcoma
topic Case Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711274/
https://www.ncbi.nlm.nih.gov/pubmed/31489209
http://dx.doi.org/10.1259/bjrcr.20170067
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