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Inferior vena cava calcification, a possible link with recurrent deep venous thrombosis and pulmonary embolism: a case study and review of literature
Inferior vena cava (IVC) anomalies have been reported to have an association with deep venous thrombosis of the lower limbs. It is, therefore, necessary to study the IVC in recurrent cases of unprovoked deep venous thrombosis (DVT) and/or pulmonary embolism (PE), where all other causes have been exc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711275/ https://www.ncbi.nlm.nih.gov/pubmed/31489221 http://dx.doi.org/10.1259/bjrcr.20180018 |
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author | Ahmed, Ahmed KA Finocchi, Vanina Al-Agib, Salah |
author_facet | Ahmed, Ahmed KA Finocchi, Vanina Al-Agib, Salah |
author_sort | Ahmed, Ahmed KA |
collection | PubMed |
description | Inferior vena cava (IVC) anomalies have been reported to have an association with deep venous thrombosis of the lower limbs. It is, therefore, necessary to study the IVC in recurrent cases of unprovoked deep venous thrombosis (DVT) and/or pulmonary embolism (PE), where all other causes have been excluded. We report a case of a 65-year-old male, who had recurrent episodes of DVT in the past 5 years; some of which associated with PE of unknown cause. CT thorax abdomen and pelvis did not find an obvious cause for the DVT and/or PE, however, it did highlight a diffuse calcification of the IVC. Only a few cases of calcification of the IVC have been reported in literature, and a number of them have been associated with clot formation and PE. We speculate that, as in other anomalies of the IVC, calcification of the IVC might slow the blood flow, and thus predispose to DVT and/or PE. Our opinion is that in all cases of unexplained DVT and/or PE, a careful examination of the IVC should be performed. Furthermore, when this condition is present, other risk factors for hypercoagulability should be avoided and anticoagulant therapy should be considered. |
format | Online Article Text |
id | pubmed-6711275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67112752019-09-05 Inferior vena cava calcification, a possible link with recurrent deep venous thrombosis and pulmonary embolism: a case study and review of literature Ahmed, Ahmed KA Finocchi, Vanina Al-Agib, Salah BJR Case Rep Case Report Inferior vena cava (IVC) anomalies have been reported to have an association with deep venous thrombosis of the lower limbs. It is, therefore, necessary to study the IVC in recurrent cases of unprovoked deep venous thrombosis (DVT) and/or pulmonary embolism (PE), where all other causes have been excluded. We report a case of a 65-year-old male, who had recurrent episodes of DVT in the past 5 years; some of which associated with PE of unknown cause. CT thorax abdomen and pelvis did not find an obvious cause for the DVT and/or PE, however, it did highlight a diffuse calcification of the IVC. Only a few cases of calcification of the IVC have been reported in literature, and a number of them have been associated with clot formation and PE. We speculate that, as in other anomalies of the IVC, calcification of the IVC might slow the blood flow, and thus predispose to DVT and/or PE. Our opinion is that in all cases of unexplained DVT and/or PE, a careful examination of the IVC should be performed. Furthermore, when this condition is present, other risk factors for hypercoagulability should be avoided and anticoagulant therapy should be considered. The British Institute of Radiology. 2018-04-16 /pmc/articles/PMC6711275/ /pubmed/31489221 http://dx.doi.org/10.1259/bjrcr.20180018 Text en © 2018 The Authors. Published by the British Institute of Radiology http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Case Report Ahmed, Ahmed KA Finocchi, Vanina Al-Agib, Salah Inferior vena cava calcification, a possible link with recurrent deep venous thrombosis and pulmonary embolism: a case study and review of literature |
title | Inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
title_full | Inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
title_fullStr | Inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
title_full_unstemmed | Inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
title_short | Inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
title_sort | inferior vena cava calcification, a possible link with recurrent deep
venous thrombosis and pulmonary embolism: a case study and review of
literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711275/ https://www.ncbi.nlm.nih.gov/pubmed/31489221 http://dx.doi.org/10.1259/bjrcr.20180018 |
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