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Cohort study of microelement status in “healthy” population of Russian megapolis
The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subj...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
EDP Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711323/ https://www.ncbi.nlm.nih.gov/pubmed/31453796 http://dx.doi.org/10.1051/bmdcn/2019090315 |
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author | Martusevich, Andrew K. Karuzin, Konstantin A. |
author_facet | Martusevich, Andrew K. Karuzin, Konstantin A. |
author_sort | Martusevich, Andrew K. |
collection | PubMed |
description | The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subjects was standardized by age and gender. A blood sample was taken once from each person to determine concentrations of microelements. The level of peripheral blood microelements were determined by atomic absorption spectrometry using «Shimadzu AA7000» device (Japan). The study of a large population of city residents demonstrated inhomogeneity in their microelement status. Deficit conditions were found for a number of values, including concentrations of potassium, sodium, nickel, stibium, chromium and cadmium. At the same time, there are large proportions of persons with low plasma concentrations of copper and even lower plasma concentrations of zinc and magnesium. On the contrary, 42% of the persons show high concentrations of lithium. Such disturbances of microelement homeostasis (pre-pathological condition) make it necessary to perform targeted correction for the purpose of preventing the development of pathological conditions associated with microelement deficiencies. |
format | Online Article Text |
id | pubmed-6711323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | EDP Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-67113232019-09-12 Cohort study of microelement status in “healthy” population of Russian megapolis Martusevich, Andrew K. Karuzin, Konstantin A. Biomedicine (Taipei) Short Communication The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subjects was standardized by age and gender. A blood sample was taken once from each person to determine concentrations of microelements. The level of peripheral blood microelements were determined by atomic absorption spectrometry using «Shimadzu AA7000» device (Japan). The study of a large population of city residents demonstrated inhomogeneity in their microelement status. Deficit conditions were found for a number of values, including concentrations of potassium, sodium, nickel, stibium, chromium and cadmium. At the same time, there are large proportions of persons with low plasma concentrations of copper and even lower plasma concentrations of zinc and magnesium. On the contrary, 42% of the persons show high concentrations of lithium. Such disturbances of microelement homeostasis (pre-pathological condition) make it necessary to perform targeted correction for the purpose of preventing the development of pathological conditions associated with microelement deficiencies. EDP Sciences 2019-08-26 /pmc/articles/PMC6711323/ /pubmed/31453796 http://dx.doi.org/10.1051/bmdcn/2019090315 Text en © Author(s) 2019. This article is published with open access by China Medical University Open Access This article is distributed under terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits any use, distribution, and reproduction in any medium, provided original author(s) and source are credited. |
spellingShingle | Short Communication Martusevich, Andrew K. Karuzin, Konstantin A. Cohort study of microelement status in “healthy” population of Russian megapolis |
title | Cohort study of microelement status in “healthy” population of Russian megapolis |
title_full | Cohort study of microelement status in “healthy” population of Russian megapolis |
title_fullStr | Cohort study of microelement status in “healthy” population of Russian megapolis |
title_full_unstemmed | Cohort study of microelement status in “healthy” population of Russian megapolis |
title_short | Cohort study of microelement status in “healthy” population of Russian megapolis |
title_sort | cohort study of microelement status in “healthy” population of russian megapolis |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711323/ https://www.ncbi.nlm.nih.gov/pubmed/31453796 http://dx.doi.org/10.1051/bmdcn/2019090315 |
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