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Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia

BACKGROUND: Population-based coronary heart disease (CHD) studies have focused on myocardial infarction (MI) with limited data on trends across the spectrum of CHD. We investigated trends in hospitalisation rates for acute and chronic CHD subgroups in England and Australia from 1996 to 2013. METHODS...

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Autores principales: Nedkoff, Lee, Goldacre, Raphael, Greenland, Melanie, Goldacre, Michael J, Lopez, Derrick, Hall, Nick, Knuiman, Matthew, Hobbs, Michael, Sanfilippo, Frank M, Wright, F Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711344/
https://www.ncbi.nlm.nih.gov/pubmed/30948515
http://dx.doi.org/10.1136/heartjnl-2018-314512
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author Nedkoff, Lee
Goldacre, Raphael
Greenland, Melanie
Goldacre, Michael J
Lopez, Derrick
Hall, Nick
Knuiman, Matthew
Hobbs, Michael
Sanfilippo, Frank M
Wright, F Lucy
author_facet Nedkoff, Lee
Goldacre, Raphael
Greenland, Melanie
Goldacre, Michael J
Lopez, Derrick
Hall, Nick
Knuiman, Matthew
Hobbs, Michael
Sanfilippo, Frank M
Wright, F Lucy
author_sort Nedkoff, Lee
collection PubMed
description BACKGROUND: Population-based coronary heart disease (CHD) studies have focused on myocardial infarction (MI) with limited data on trends across the spectrum of CHD. We investigated trends in hospitalisation rates for acute and chronic CHD subgroups in England and Australia from 1996 to 2013. METHODS: CHD hospitalisations for individuals aged 35–84 years were identified from electronic hospital data from 1996 to 2013 for England and Australia and from the Oxford Region and Western Australia. CHD subgroups identified were acute coronary syndromes (ACS) (MI and unstable angina) and chronic CHD (stable angina and ‘other CHD’). We calculated age-standardised and age-specific rates and estimated annual changes (95% CI) from age-adjusted Poisson regression. RESULTS: From 1996 to 2013, there were 4.9 million CHD hospitalisations in England and 2.6 million in Australia (67% men). From 1996 to 2003, there was between-country variation in the direction of trends in ACS and chronic CHD hospitalisation rates (p<0.001). During 2004–2013, reductions in ACS hospitalisation rates were greater than for chronic CHD hospitalisation rates in both countries, with the largest subgroup declines in unstable angina (England: men: −7.1 %/year, 95% CI −7.2 to –7.0; women: −7.5 %/year, 95% CI −7.7 to –7.3; Australia: men: −8.5 %/year, 95% CI −8.6 to –8.4; women: −8.6 %/year, 95% CI −8.8 to –8.4). Other CHD rates increased in individuals aged 75–84 years in both countries. Chronic CHD comprised half of all CHD admissions, with the majority involving angiography or percutaneous coronary intervention. CONCLUSIONS: Since 2004, rates of all CHD subgroups have fallen, with greater declines in acute than chronic presentations. The slower declines and high proportion of chronic CHD admissions undergoing coronary procedures requires greater focus.
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spelling pubmed-67113442019-09-09 Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia Nedkoff, Lee Goldacre, Raphael Greenland, Melanie Goldacre, Michael J Lopez, Derrick Hall, Nick Knuiman, Matthew Hobbs, Michael Sanfilippo, Frank M Wright, F Lucy Heart Coronary Artery Disease BACKGROUND: Population-based coronary heart disease (CHD) studies have focused on myocardial infarction (MI) with limited data on trends across the spectrum of CHD. We investigated trends in hospitalisation rates for acute and chronic CHD subgroups in England and Australia from 1996 to 2013. METHODS: CHD hospitalisations for individuals aged 35–84 years were identified from electronic hospital data from 1996 to 2013 for England and Australia and from the Oxford Region and Western Australia. CHD subgroups identified were acute coronary syndromes (ACS) (MI and unstable angina) and chronic CHD (stable angina and ‘other CHD’). We calculated age-standardised and age-specific rates and estimated annual changes (95% CI) from age-adjusted Poisson regression. RESULTS: From 1996 to 2013, there were 4.9 million CHD hospitalisations in England and 2.6 million in Australia (67% men). From 1996 to 2003, there was between-country variation in the direction of trends in ACS and chronic CHD hospitalisation rates (p<0.001). During 2004–2013, reductions in ACS hospitalisation rates were greater than for chronic CHD hospitalisation rates in both countries, with the largest subgroup declines in unstable angina (England: men: −7.1 %/year, 95% CI −7.2 to –7.0; women: −7.5 %/year, 95% CI −7.7 to –7.3; Australia: men: −8.5 %/year, 95% CI −8.6 to –8.4; women: −8.6 %/year, 95% CI −8.8 to –8.4). Other CHD rates increased in individuals aged 75–84 years in both countries. Chronic CHD comprised half of all CHD admissions, with the majority involving angiography or percutaneous coronary intervention. CONCLUSIONS: Since 2004, rates of all CHD subgroups have fallen, with greater declines in acute than chronic presentations. The slower declines and high proportion of chronic CHD admissions undergoing coronary procedures requires greater focus. BMJ Publishing Group 2019-09 2019-04-04 /pmc/articles/PMC6711344/ /pubmed/30948515 http://dx.doi.org/10.1136/heartjnl-2018-314512 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Coronary Artery Disease
Nedkoff, Lee
Goldacre, Raphael
Greenland, Melanie
Goldacre, Michael J
Lopez, Derrick
Hall, Nick
Knuiman, Matthew
Hobbs, Michael
Sanfilippo, Frank M
Wright, F Lucy
Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title_full Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title_fullStr Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title_full_unstemmed Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title_short Comparative trends in coronary heart disease subgroup hospitalisation rates in England and Australia
title_sort comparative trends in coronary heart disease subgroup hospitalisation rates in england and australia
topic Coronary Artery Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711344/
https://www.ncbi.nlm.nih.gov/pubmed/30948515
http://dx.doi.org/10.1136/heartjnl-2018-314512
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