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Application of Bayesian predictive probability for interim futility analysis in single-arm phase II trial
BACKGROUND: Bayesian predictive probability design, with a binary endpoint, is gaining attention for the phase II trial due to its innovative strategy. To make the Bayesian design more accessible, we elucidate this Bayesian approach with a R package to streamline a statistical plan, so biostatistici...
Autores principales: | Chen, Dung-Tsa, Schell, Michael J., Fulp, William J., Pettersson, Fredrik, Kim, Sungjune, Gray, Jhanelle E., Haura, Eric B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711387/ https://www.ncbi.nlm.nih.gov/pubmed/31456910 http://dx.doi.org/10.21037/tcr.2019.05.17 |
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