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Inhibition of the hedgehog pathway for the treatment of cancer using Itraconazole

Itraconazole (ITZ) is an anti-fungal drug that has been used in clinical practice for nearly 35 years. Recently, numerous experiments have shown that ITZ possesses anti-cancer properties. The Hedgehog (Hh) pathway plays a pivotal role in fundamental processes, including embryogenesis, structure, mor...

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Detalles Bibliográficos
Autores principales: Li, Ke, Fang, Dengyang, Xiong, Zuming, Luo, Runlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711563/
https://www.ncbi.nlm.nih.gov/pubmed/31692536
http://dx.doi.org/10.2147/OTT.S223119