Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test

INTRODUCTION: Syphilis rapid test results may be influenced by numerous environmental and genetic factors. METHODS: The proportion of false positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from Cameroonian blacks (n=...

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Autores principales: Mbopi-Keou, Francois-Xavier, Kalla, Ginette Claude Mireille, Voundi, Esther Voundi, Jenabian, Mohammad-Ali, Mboumba Bouassa, Ralph-Sydney, Talla, Frédéric, Angwafo, Fru F, Belec, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711684/
https://www.ncbi.nlm.nih.gov/pubmed/31489068
http://dx.doi.org/10.11604/pamj.2019.33.90.16437
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author Mbopi-Keou, Francois-Xavier
Kalla, Ginette Claude Mireille
Voundi, Esther Voundi
Jenabian, Mohammad-Ali
Mboumba Bouassa, Ralph-Sydney
Talla, Frédéric
Angwafo, Fru F
Belec, Laurent
author_facet Mbopi-Keou, Francois-Xavier
Kalla, Ginette Claude Mireille
Voundi, Esther Voundi
Jenabian, Mohammad-Ali
Mboumba Bouassa, Ralph-Sydney
Talla, Frédéric
Angwafo, Fru F
Belec, Laurent
author_sort Mbopi-Keou, Francois-Xavier
collection PubMed
description INTRODUCTION: Syphilis rapid test results may be influenced by numerous environmental and genetic factors. METHODS: The proportion of false positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from Cameroonian blacks (n=103) versus French blacks (n=104) or French caucasians (n=51), all HIV-negative and free of clinical syphilis, was examined. RESULTS: Black individuals in Cameroon had a significantly higher frequency of false positive NT or T tests than black individuals in France. black individuals in France had a higher frequency of indeterminate NT tests as compared to caucasians in France. CONCLUSION: Both racial and environmental factors may affect immuno-chromatographic dual syphilis rapid testing.
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spelling pubmed-67116842019-09-05 Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test Mbopi-Keou, Francois-Xavier Kalla, Ginette Claude Mireille Voundi, Esther Voundi Jenabian, Mohammad-Ali Mboumba Bouassa, Ralph-Sydney Talla, Frédéric Angwafo, Fru F Belec, Laurent Pan Afr Med J Research INTRODUCTION: Syphilis rapid test results may be influenced by numerous environmental and genetic factors. METHODS: The proportion of false positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from Cameroonian blacks (n=103) versus French blacks (n=104) or French caucasians (n=51), all HIV-negative and free of clinical syphilis, was examined. RESULTS: Black individuals in Cameroon had a significantly higher frequency of false positive NT or T tests than black individuals in France. black individuals in France had a higher frequency of indeterminate NT tests as compared to caucasians in France. CONCLUSION: Both racial and environmental factors may affect immuno-chromatographic dual syphilis rapid testing. The African Field Epidemiology Network 2019-06-06 /pmc/articles/PMC6711684/ /pubmed/31489068 http://dx.doi.org/10.11604/pamj.2019.33.90.16437 Text en © Francois-Xavier Mbopi-Keou et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Mbopi-Keou, Francois-Xavier
Kalla, Ginette Claude Mireille
Voundi, Esther Voundi
Jenabian, Mohammad-Ali
Mboumba Bouassa, Ralph-Sydney
Talla, Frédéric
Angwafo, Fru F
Belec, Laurent
Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title_full Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title_fullStr Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title_full_unstemmed Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title_short Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
title_sort differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711684/
https://www.ncbi.nlm.nih.gov/pubmed/31489068
http://dx.doi.org/10.11604/pamj.2019.33.90.16437
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