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Aging-associated impairment in metabolic compensation by subcutaneous adipose tissue promotes diet-induced fatty liver disease in mice
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome, and its progression is associated with aging-associated impairment in metabolic homeostasis. Recently, energy metabolism in adipose tissue has been the subject of renewed interest, because...
Autores principales: | Taketani, Hiroyoshi, Nishikawa, Taichiro, Nakajima, Hisakazu, Kodo, Kazuki, Sugimoto, Satoru, Aoi, Wataru, Horike, Shin-ichi, Meguro-Horike, Makiko, Ishiba, Hiroshi, Seko, Yuya, Umemura, Atsushi, Yamaguchi, Kanji, Moriguchi, Michihisa, Yasui, Kohichiroh, Itoh, Yoshito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711723/ https://www.ncbi.nlm.nih.gov/pubmed/31692556 http://dx.doi.org/10.2147/DMSO.S214093 |
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