The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake

BACKGROUND: The imprinted gene Delta like non-canonical Notch ligand 1 (Dlk1) is considered an inhibitor of adipogenesis, but its in vivo impact on fat mass indeed remains elusive and controversial. METHODS: Fat deposits were assessed by MRI and DXA scanning in two cohorts of non-diabetic men, where...

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Detalles Bibliográficos
Autores principales: Jensen, Charlotte Harken, Kosmina, Rok, Rydén, Mikael, Baun, Christina, Hvidsten, Svend, Andersen, Marianne Skovsager, Christensen, Louise Lehmann, Gastaldelli, Amalia, Marraccini, Paolo, Arner, Peter, Jørgensen, Christian Damsgaard, Laborda, Jorge, Holst, Jens Juul, Andersen, Ditte Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711890/
https://www.ncbi.nlm.nih.gov/pubmed/31383551
http://dx.doi.org/10.1016/j.ebiom.2019.07.070

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