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RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

Recent studies have proposed that nucleic acids act as potential cofactors for protein aggregation and prionogenesis. By means of sedimentation, transmission electron microscopy, circular dichroism, static and dynamic light scattering, we have studied how RNA can influence the aggregation of the mur...

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Detalles Bibliográficos
Autores principales:	Kovachev, Petar Stefanov, Gomes, Mariana P. B., Cordeiro, Yraima, Ferreira, Natália C., Valadão, Leticia P. Felix, Ascari, Lucas M., Rangel, Luciana P., Silva, Jerson L., Sanyal, Suparna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712051/ https://www.ncbi.nlm.nih.gov/pubmed/31455808 http://dx.doi.org/10.1038/s41598-019-48883-x

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