云南省昆明市城市居民肺癌筛查结果分析

BACKGROUND AND OBJECTIVE: Lung cancer screening is an effective measure to reduce lung cancer mortality. Currently, lung cancer screening is recommended internationally and nationally. China had launched a large-scale early diagnosis and early treatment of rural and urban lung cancer in 2009 and 2012. Yunnan Province participated in related projects in 2009 and 2014, but the results of large-scale lung cancer screening have not been reported in Yunnan Province. In this study, we participated in the National Key Public Health Program, Cancer Screening Program in Urban China and analyzed the results of lung cancer screening in 10, 154 urban residents in Kunming, Yunnan Province from 2014 to 2018, and evaluated the screening effect of early diagnosis and treatment of lung cancer in urban. METHODS: A total of 31, 824 people with high risk of lung cancer were evaluated with 40-74 year-old population in Kunming. A high-risk group underwent low-dose spiral computed tomography (CT) scan of the chest, and analyze the high risk rate and detection rate. A total of 150, 535 questionnaires were completed in 5 years, and 31, 824 people with high risk of lung cancer were evaluated. RESULTS: The high-risk rate was 21.14%. A total of 10, 154 low-dose spiral CT screenings were performed, with a participation rate of 31.91%. The detection rate of intrapulmonary nodules was 22.28% (2, 262/10, 154), of which the detection rate of < 5 mm solid/partial solid nodules was 11.30% (1, 332/10, 154) and the detection rate of < 8 mm non-solid nodules was 2.20% (219/10, 154). The positive nodule detection rate was 7.00% (711/10, 154), the suspected lung cancer detection rate was 0.60% (59/10, 154), and the lung cancer detection rate was 0.27% (27/10, 154). The detection rate of the positive nodules, < 8 mm non-solid nodules and suspected lung cancer in male were significantly higher than that in female, and the positive nodules, < 5 mm solid nodules, suspected lung cancer and confirmed lung cancer detection rate increased with age. CONCLUSION: Low-dose spiral CT is suitable for screening of high-risk populations of lung cancer, which is helpful for early detection of positive nodules and related diseases in the lungs. It is necessary to pay attention to the screening of lung cancer in people over 60 years old. Understand the lung health status of residents in Kunming. Raise awareness of lung cancer prevention and treatment among residents, and improve the rate of early diagnosis and treatment of lung cancer.