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ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53

Macrophages and dendritic cells dominate early immune responses to lentiviruses. HIV-1 sensing by pathogen recognition receptors induces signaling cascades that culminate in type I alpha/beta interferon (IFN-α/β) induction. IFN-α/β signals back via the IFN-α/β receptors, inducing a plethora of IFN-s...

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Detalles Bibliográficos
Autores principales:	Osei Kuffour, Edmund, König, Renate, Häussinger, Dieter, Schulz, Wolfgang A., Münk, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712392/ https://www.ncbi.nlm.nih.gov/pubmed/31455647 http://dx.doi.org/10.1128/mBio.01342-19

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