Significantly increased anti‐tumor activity of carcinoembryonic antigen‐specific chimeric antigen receptor T cells in combination with recombinant human IL‐12

BACKGROUND AIMS: Chimeric antigen receptor T cells (CAR‐T cells) have been successfully used in treatments of hematological tumors, however, their anti‐tumor activity in solid tumor treatments was limited. As IL‐12 increases T‐cell immune functions, we designed carcinoembryonic antigen (CEA) specifi...

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Detalles Bibliográficos
Autores principales: Chi, Xiaowei, Yang, Peiwei, Zhang, Erhao, Gu, Jieyi, Xu, Hui, Li, Mengwei, Gao, Xinmei, Li, Xin, Zhang, Yinan, Xu, Hanmei, Hu, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712469/
https://www.ncbi.nlm.nih.gov/pubmed/31237116
http://dx.doi.org/10.1002/cam4.2361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712469/
https://www.ncbi.nlm.nih.gov/pubmed/31237116
http://dx.doi.org/10.1002/cam4.2361

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