Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K‐Akt signaling in gastric cancer

BACKGROUND: As the most abundant epigenetic modification on mRNAs and long non‐coding RNAs, N6‐methyladenosine (m6A) modification extensively exists in mammalian cells. Controlled by writers (methyltransferases), readers (signal transducers), and erasers (demethylases), m6A influences mRNA structure...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Zhang, Mengqi, Ge, Sai, Huang, Wenwen, Lin, Xiaoting, Gao, Jing, Gong, Jifang, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712480/
https://www.ncbi.nlm.nih.gov/pubmed/31243897
http://dx.doi.org/10.1002/cam4.2360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712480/
https://www.ncbi.nlm.nih.gov/pubmed/31243897
http://dx.doi.org/10.1002/cam4.2360

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