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Human T Cell Differentiation Negatively Regulates Telomerase Expression Resulting in Reduced Activation-Induced Proliferation and Survival
Maintenance of telomeres is essential for preserving T cell proliferative responses yet the precise role of telomerase in human T cell differentiation, function, and aging is not fully understood. Here we analyzed human telomerase reverse transcriptase (hTERT) expression and telomerase activity in s...
Autores principales: | Patrick, Michael S., Cheng, Nai-Lin, Kim, Jaekwan, An, Jie, Dong, Fangyuan, Yang, Qian, Zou, Iris, Weng, Nan-ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712505/ https://www.ncbi.nlm.nih.gov/pubmed/31497023 http://dx.doi.org/10.3389/fimmu.2019.01993 |
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