Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01)

BACKGROUND: Adjuvant bisphosphonates are associated with improved breast cancer survival in postmenopausal patients. Addition of zoledronic acid (ZA) to neoadjuvant chemotherapy did not improve pathological complete response in the phase III NEOZOTAC trial. Here we report the results of the secondar...

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Detalles Bibliográficos
Autores principales: de Groot, Stefanie, Pijl, Hanno, Charehbili, Ayoub, van de Ven, Saskia, Smit, Vincent T. H. B. M., Meershoek-Klein Kranenbarg, Elma, Heijns, Joan B., van Warmerdam, Laurence J. C., Kessels, Lonneke W., Dercksen, M. Wouter, Pepels, Manon J. A. E., van Laarhoven, Hanneke W. M., Vriens, Birgit E. P. J., Putter, Hein, Fiocco, Marta, Liefers, Gerrit-Jan, van der Hoeven, Jacobus J. M., Nortier, Johan W. R., Kroep, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712613/
https://www.ncbi.nlm.nih.gov/pubmed/31455425
http://dx.doi.org/10.1186/s13058-019-1180-6

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