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Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro

BACKGROUND: Oligodendrocytes are a type of glial cells that synthesize the myelin sheath around the axons and are critical for the nerve conduction in the CNS. Oligodendrocyte death and defects are the leading causes of several myelin disorders such as multiple sclerosis, progressive multifocal leuk...

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Detalles Bibliográficos
Autores principales:	Namchaiw, Poommaree, Wen, Han, Mayrhofer, Florian, Chechneva, Olga, Biswas, Sangita, Deng, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712625/ https://www.ncbi.nlm.nih.gov/pubmed/31455382 http://dx.doi.org/10.1186/s13287-019-1374-y

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