Immature O-glycans recognized by the macrophage glycoreceptor CLEC10A (MGL) are induced by 4-hydroxy-tamoxifen, oxidative stress and DNA-damage in breast cancer cells

BACKGROUND: Ligands of the C-type lectin CLEC10A such as Tn and sialyl-Tn representing early intermediates of O-glycosylation are hallmarks of many human malignancies. A variety of regulatory mechanisms underlying their expression are being discussed. METHODS: CLEC10A ligands were detected in variou...

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Detalles Bibliográficos
Autores principales: Kurze, Anna-Katharina, Buhs, Sophia, Eggert, Dennis, Oliveira-Ferrer, Leticia, Müller, Volkmar, Niendorf, Axel, Wagener, Christoph, Nollau, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712659/
https://www.ncbi.nlm.nih.gov/pubmed/31455323
http://dx.doi.org/10.1186/s12964-019-0420-9

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