Telomere alterations in neurofibromatosis type 1-associated solid tumors

The presence of Alternative lengthening of telomeres (ALT) and/or ATRX loss, as well as the role of other telomere abnormalities, have not been formally studied across the spectrum of NF1-associated solid tumors. Utilizing a telomere-specific FISH assay, we classified tumors as either ALT-positive o...

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Detalles Bibliográficos
Autores principales: Rodriguez, Fausto J., Graham, Mindy K., Brosnan-Cashman, Jacqueline A., Barber, John R., Davis, Christine, Vizcaino, M. Adelita, Palsgrove, Doreen N., Giannini, Caterina, Pekmezci, Melike, Dahiya, Sonika, Gokden, Murat, Noë, Michael, Wood, Laura D., Pratilas, Christine A., Morris, Carol D., Belzberg, Allan, Blakeley, Jaishri, Heaphy, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712691/
https://www.ncbi.nlm.nih.gov/pubmed/31462295
http://dx.doi.org/10.1186/s40478-019-0792-5

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