Cargando…

Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET

BACKGROUND: Alterations in the expression of human kallikrein-related peptidases (KLKs) have been described in patients with Alzheimer’s disease (AD). We elucidated the suitability of KLK6, KLK8 and KLK10 to distinguish AD from NC and explored associations with established AD biomarkers. METHODS: KL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goldhardt, Oliver, Warnhoff, Inanna, Yakushev, Igor, Begcevic, Ilijana, Förstl, Hans, Magdolen, Viktor, Soosaipillai, Antoninus, Diamandis, Eleftherios, Alexopoulos, Panagiotis, Grimmer, Timo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712703/ https://www.ncbi.nlm.nih.gov/pubmed/31467673 http://dx.doi.org/10.1186/s40035-019-0168-6

Ejemplares similares

Aberrant expression of kallikrein‐related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion
por: Delaunay, Tiphaine, et al.
Publicado: (2017)

Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer’s disease
por: Patra, Kalicharan, et al.
Publicado: (2018)

A new enzyme-linked immunosorbent assay (ELISA) for human free and bound kallikrein 9
por: Filippou, Panagiota, et al.
Publicado: (2017)

Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the Human Protein Atlas
por: Begcevic, Ilijana, et al.
Publicado: (2016)

The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer
por: Talieri, M, et al.
Publicado: (2009)

Emerging clinical importance of the cancer biomarkers kallikrein-related peptidases (KLK) in female and male reproductive organ malignancies
por: Schmitt, Manfred, et al.
Publicado: (2013)

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
por: Goettig, Peter, et al.
Publicado: (2010)

Prognostic value of kallikrein-related peptidase 7 (KLK7) mRNA expression in advanced high-grade serous ovarian cancer
por: Gong, Weiwei, et al.
Publicado: (2020)

Quantitative assessment and clinical relevance of kallikrein-related peptidase 5 mRNA expression in advanced high-grade serous ovarian cancer
por: Gong, Weiwei, et al.
Publicado: (2019)

Amyloid PET, FDG-PET or MRI? - the power of different imaging biomarkers to detect progression of early Alzheimer’s disease
por: Ortner, Marion, et al.
Publicado: (2019)

Correction to: Amyloid PET, FDG-PET or MRI? - the power of different imaging biomarkers to detect progression of early Alzheimer’s disease
por: Ortner, Marion, et al.
Publicado: (2020)

Discovery of novel plasma biomarker ratios to discriminate traumatic brain injury
por: Chen, Michelle, et al.
Publicado: (2019)

Structural basis for the Zn(2+) inhibition of the zymogen-like kallikrein-related peptidase 10
por: Debela, Mekdes, et al.
Publicado: (2016)

Kallikrein gene downregulation in breast cancer
por: Yousef, G M, et al.
Publicado: (2004)

Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis
por: Bouzid, Hayet, et al.
Publicado: (2022)

Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma
por: Candido, Juliana B., et al.
Publicado: (2021)

Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer’s disease and age-matched control brains
por: Begcevic, Ilijana, et al.
Publicado: (2013)

Elecsys Cerebrospinal Fluid Immunoassays Accurately Detect Alzheimer’s Disease Regardless of Concomitant Small Vessel Disease
por: Ortner, Marion, et al.
Publicado: (2023)

Correction to: A proteome-wide immuno-mass spectrometric identification of serum autoantibodies
por: Music, Milena, et al.
Publicado: (2019)

A proteome-wide immuno-mass spectrometric identification of serum autoantibodies
por: Music, Milena, et al.
Publicado: (2019)

Neuronal pentraxin receptor-1 is a new cerebrospinal fluid biomarker of Alzheimer’s disease progression
por: Begcevic, Ilijana, et al.
Publicado: (2018)

Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity
por: Skala, Wolfgang, et al.
Publicado: (2014)

Comparison of two multiplexed technologies for profiling >1,000 serum proteins that may associate with tumor burden
por: Ren, Annie, et al.
Publicado: (2021)

A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity
por: Skala, Wolfgang, et al.
Publicado: (2016)

Kallikrein 6 as a Serum Prognostic Marker in Patients with Aneurysmal Subarachnoid Hemorrhage
por: Martínez-Morillo, Eduardo, et al.
Publicado: (2012)

Higher expression of human kallikrein 10 in breast cancer tissue predicts tamoxifen resistance
por: Luo, L-Y, et al.
Publicado: (2002)

Investigating a novel multiplex proteomics technology for detection of changes in serum protein concentrations that may correlate to tumor burden
por: Ren, Annie He, et al.
Publicado: (2020)

Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer
por: Wang, Ping, et al.
Publicado: (2018)

Prognostic significance of multiple kallikreins in high-grade astrocytoma
por: Drucker, Kristen L., et al.
Publicado: (2015)

Metastasis of ovarian cancer is mediated by kallikrein related peptidases
por: Dong, Ying, et al.
Publicado: (2013)

Involvement of Kallikrein-Related Peptidases in Normal and Pathologic Processes
por: Stefanini, Ana Carolina B., et al.
Publicado: (2015)

Involvement of Kallikrein-Related Peptidases in Nervous System Disorders
por: Mella, Cinthia, et al.
Publicado: (2020)

Prognostic value of kallikrein-related peptidase 12 (KLK12) mRNA expression in triple-negative breast cancer patients
por: Gong, Weiwei, et al.
Publicado: (2020)

Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer
por: Geng, Xiaocong, et al.
Publicado: (2017)

Secretome and degradome profiling shows that Kallikrein‐related peptidases 4, 5, 6, and 7 induce TGFβ‐1 signaling in ovarian cancer cells
por: Shahinian, Hasmik, et al.
Publicado: (2013)

Expression of kallikrein-related peptidase 7 is decreased in prostate cancer
por: Zhang, Chong-Yu, et al.
Publicado: (2015)

Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients
por: Gong, Weiwei, et al.
Publicado: (2019)

The cerebrospinal fluid biomarker ratio Aβ42/40 identifies amyloid positron emission tomography positivity better than Aβ42 alone in a heterogeneous memory clinic cohort
por: Amft, Michaela, et al.
Publicado: (2022)

Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9
por: Makawita, Shalini, et al.
Publicado: (2013)

Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line
por: Vasiliou, Stella K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qmrjpp4m2r8n42prg4g5qiaosv