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Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage

BACKGROUND: Gouty arthritis is characterized by the deposition of monosodium urate (MSU) within synovial joints and tissues due to increased urate concentrations. In this study, we explored the effect of the natural compound curcumin on the MSU crystal-stimulated inflammatory response. METHODS: THP-...

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Detalles Bibliográficos
Autores principales:	Chen, Baofeng, Li, Hongmei, Ou, Guochun, Ren, Long, Yang, Xiaohong, Zeng, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712780/ https://www.ncbi.nlm.nih.gov/pubmed/31455356 http://dx.doi.org/10.1186/s13075-019-1974-z

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