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Frequent retrotransposition of endogenous genes in ERCC2-deficient cells derived from a patient with xeroderma pigmentosum
BACKGROUND: Retrotransposition of protein-coding genes is thought to occur due to the existence of numerous processed pseudogenes in both animals and plants. Unlike retrotransposons including Alu and LINE-1, direct evidence of such retrotransposition events has not been reported to date. Even if suc...
Autores principales: | Aoto, Saki, Katagiri, Saki, Wang, Yi, Pagnamenta, Alistair T., Sakamoto-Abutani, Rie, Toyoda, Masashi, Umezawa, Akihiro, Okamura, Kohji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712803/ https://www.ncbi.nlm.nih.gov/pubmed/31455402 http://dx.doi.org/10.1186/s13287-019-1381-z |
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