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Influence of androgenic blockade with flutamide on pain behaviour and expression of the genes that encode the NaV1.7 and NaV1.8 voltage-dependent sodium channels in a rat model of postoperative pain

BACKGROUND: Experimental studies suggest that testosterone reduces the nociceptive response after inflammatory and neuropathic stimuli, however the underlying mechanisms have not been fully elucidated. The aims of this study were to evaluate the effect of peripheral blockade of testosterone on pain...

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Detalles Bibliográficos
Autores principales:	Barbosa Neto, José Osvaldo, Garcia, João Batista Santos, Cartágenes, Maria do Socorro de Souza, Amaral, Andressa Godoy, Onuchic, Luiz Fernando, Ashmawi, Hazem Adel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712891/ https://www.ncbi.nlm.nih.gov/pubmed/31455381 http://dx.doi.org/10.1186/s12967-019-2031-z

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