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Curcumin Inhibits Joint Contracture through PTEN Demethylation and Targeting PI3K/Akt/mTOR Pathway in Myofibroblasts from Human Joint Capsule

Joint contracture is increasingly regarded as a clinical problem that leads to irreversible dysfunction of the joint. It is a pathophysiological process following joint injury, which is marked by the activation of myofibroblasts. There is currently no effective treatment for the prevention of joint...

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Detalles Bibliográficos
Autores principales: Zhuang, Ze, Yu, Dongjie, Chen, Zheng, Liu, Dezhao, Yuan, Guohui, Yirong, Ni, Sun, Linlin, Liu, Yuangao, He, Ronghan, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712967/
https://www.ncbi.nlm.nih.gov/pubmed/31511778
http://dx.doi.org/10.1155/2019/4301238