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Curcumin Inhibits Joint Contracture through PTEN Demethylation and Targeting PI3K/Akt/mTOR Pathway in Myofibroblasts from Human Joint Capsule
Joint contracture is increasingly regarded as a clinical problem that leads to irreversible dysfunction of the joint. It is a pathophysiological process following joint injury, which is marked by the activation of myofibroblasts. There is currently no effective treatment for the prevention of joint...
Autores principales: | Zhuang, Ze, Yu, Dongjie, Chen, Zheng, Liu, Dezhao, Yuan, Guohui, Yirong, Ni, Sun, Linlin, Liu, Yuangao, He, Ronghan, Wang, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712967/ https://www.ncbi.nlm.nih.gov/pubmed/31511778 http://dx.doi.org/10.1155/2019/4301238 |
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