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Targeting murine alveolar macrophages by the intratracheal administration of locked nucleic acid containing antisense oligonucleotides

The pulmonary delivery of locked nucleic acid containing antisense oligonucleotides (LNA-ASOs) is expected to be a novel therapeutic approach for lung diseases. However, there are two concerns to be considered: immune responses, as the lung has a distinct immune mechanism to protect it from inhaled...

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Detalles Bibliográficos
Autores principales:	Uemura, Yasunori, Kobayashi, Katsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713109/ https://www.ncbi.nlm.nih.gov/pubmed/31385541 http://dx.doi.org/10.1080/10717544.2019.1648589

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