Cargando…

Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass

OBJECTIVES: Postoperative arrhythmia is an important complication of coronary artery bypass grafting (CABG) surgeries among patients. It seems that opioid usage is implicated in the pathogenesis of this condition due to its impacts on different organ systems, such as the autonomic nervous system. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Basirat, Majid, Ziyaeifard, Mohsen, Gorjipour, Farhad, Mehrabanian, Mohammad Javad, Attarzadeh, Seyed Hassan, Nekoofard, Majid, Mortazian, Meysam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713381/
https://www.ncbi.nlm.nih.gov/pubmed/31454198
http://dx.doi.org/10.21470/1678-9741-2018-0392
_version_ 1783446865545527296
author Basirat, Majid
Ziyaeifard, Mohsen
Gorjipour, Farhad
Mehrabanian, Mohammad Javad
Attarzadeh, Seyed Hassan
Nekoofard, Majid
Mortazian, Meysam
author_facet Basirat, Majid
Ziyaeifard, Mohsen
Gorjipour, Farhad
Mehrabanian, Mohammad Javad
Attarzadeh, Seyed Hassan
Nekoofard, Majid
Mortazian, Meysam
author_sort Basirat, Majid
collection PubMed
description OBJECTIVES: Postoperative arrhythmia is an important complication of coronary artery bypass grafting (CABG) surgeries among patients. It seems that opioid usage is implicated in the pathogenesis of this condition due to its impacts on different organ systems, such as the autonomic nervous system. The present study was performed to investigate the effect of opium use on postoperative arrhythmia in patients undergoing CABG surgery. METHODS: Study participants were selected via convenience sampling from patients undergoing CABG surgery in a referral hospital. Study variables, including use of inotropic drugs, vital signs monitoring parameters and postoperative arrhythmia were observed and recorded at baseline and at follow-up time after surgery. RESULTS: Sixty-five (14.8%) patients had postoperative arrhythmia, and 104 participants were addicted. Prevalence of postoperative arrhythmia was the same among addict and non-addict patients. According to the regression analysis model, only serum level of epinephrine in operating room, heart rate and central venous pressure at baseline and 48 hours after operation are known as independent predictors of postoperative arrhythmia among study population. CONCLUSION: This study showed that although opium addiction increased postoperative arrhythmia among patients undergoing CABG surgery, this difference was not significant, and this association is probably mediated by other study variables.
format Online
Article
Text
id pubmed-6713381
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Sociedade Brasileira de Cirurgia Cardiovascular
record_format MEDLINE/PubMed
spelling pubmed-67133812019-09-03 Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass Basirat, Majid Ziyaeifard, Mohsen Gorjipour, Farhad Mehrabanian, Mohammad Javad Attarzadeh, Seyed Hassan Nekoofard, Majid Mortazian, Meysam Braz J Cardiovasc Surg Original Article OBJECTIVES: Postoperative arrhythmia is an important complication of coronary artery bypass grafting (CABG) surgeries among patients. It seems that opioid usage is implicated in the pathogenesis of this condition due to its impacts on different organ systems, such as the autonomic nervous system. The present study was performed to investigate the effect of opium use on postoperative arrhythmia in patients undergoing CABG surgery. METHODS: Study participants were selected via convenience sampling from patients undergoing CABG surgery in a referral hospital. Study variables, including use of inotropic drugs, vital signs monitoring parameters and postoperative arrhythmia were observed and recorded at baseline and at follow-up time after surgery. RESULTS: Sixty-five (14.8%) patients had postoperative arrhythmia, and 104 participants were addicted. Prevalence of postoperative arrhythmia was the same among addict and non-addict patients. According to the regression analysis model, only serum level of epinephrine in operating room, heart rate and central venous pressure at baseline and 48 hours after operation are known as independent predictors of postoperative arrhythmia among study population. CONCLUSION: This study showed that although opium addiction increased postoperative arrhythmia among patients undergoing CABG surgery, this difference was not significant, and this association is probably mediated by other study variables. Sociedade Brasileira de Cirurgia Cardiovascular 2019 /pmc/articles/PMC6713381/ /pubmed/31454198 http://dx.doi.org/10.21470/1678-9741-2018-0392 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Basirat, Majid
Ziyaeifard, Mohsen
Gorjipour, Farhad
Mehrabanian, Mohammad Javad
Attarzadeh, Seyed Hassan
Nekoofard, Majid
Mortazian, Meysam
Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title_full Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title_fullStr Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title_full_unstemmed Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title_short Effect of Opium Addiction on Postoperative Arrhythmia Among Patients Undergoing CABG operation on Cardiopulmonary Bypass
title_sort effect of opium addiction on postoperative arrhythmia among patients undergoing cabg operation on cardiopulmonary bypass
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713381/
https://www.ncbi.nlm.nih.gov/pubmed/31454198
http://dx.doi.org/10.21470/1678-9741-2018-0392
work_keys_str_mv AT basiratmajid effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT ziyaeifardmohsen effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT gorjipourfarhad effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT mehrabanianmohammadjavad effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT attarzadehseyedhassan effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT nekoofardmajid effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass
AT mortazianmeysam effectofopiumaddictiononpostoperativearrhythmiaamongpatientsundergoingcabgoperationoncardiopulmonarybypass