Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation, directed by local morphogen signals and mechanical cues. Here, we aimed to mimic development for regeneration of large bone defects. We hypothesized that engineered human m...

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Detalles Bibliográficos
Autores principales: Herberg, S., McDermott, A. M., Dang, P. N., Alt, D. S., Tang, R., Dawahare, J. H., Varghai, D., Shin, J.-Y., McMillan, A., Dikina, A. D., He, F., Lee, Y. B., Cheng, Y., Umemori, K., Wong, P. C., Park, H., Boerckel, J. D., Alsberg, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713501/
https://www.ncbi.nlm.nih.gov/pubmed/31489377
http://dx.doi.org/10.1126/sciadv.aax2476

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