Gastrointestinal Stromal Tumors of Small Intestine

Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract. GISTs are presumed to arise from interstitial cells of Cajal or gastrointestinal pa...

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Autores principales: Huda, Tanweerul, Singh, Mahendra Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713571/
https://www.ncbi.nlm.nih.gov/pubmed/31475241
http://dx.doi.org/10.1055/s-0039-1694704
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author Huda, Tanweerul
Singh, Mahendra Pratap
author_facet Huda, Tanweerul
Singh, Mahendra Pratap
author_sort Huda, Tanweerul
collection PubMed
description Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract. GISTs are presumed to arise from interstitial cells of Cajal or gastrointestinal pacemaker cells which control gut motility. They have unpredictable biological behavior. Prognosis is dependent on tumor size as well as mitotic count. Radical surgical excision is the treatment of choice. They rarely metastasize to lymph nodes. Imatinib therapy is used as an adjuvant therapy. The follow-up of patients postsurgery is not standardized.
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spelling pubmed-67135712019-08-30 Gastrointestinal Stromal Tumors of Small Intestine Huda, Tanweerul Singh, Mahendra Pratap Surg J (N Y) Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract. GISTs are presumed to arise from interstitial cells of Cajal or gastrointestinal pacemaker cells which control gut motility. They have unpredictable biological behavior. Prognosis is dependent on tumor size as well as mitotic count. Radical surgical excision is the treatment of choice. They rarely metastasize to lymph nodes. Imatinib therapy is used as an adjuvant therapy. The follow-up of patients postsurgery is not standardized. Thieme Medical Publishers 2019-08-28 /pmc/articles/PMC6713571/ /pubmed/31475241 http://dx.doi.org/10.1055/s-0039-1694704 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Huda, Tanweerul
Singh, Mahendra Pratap
Gastrointestinal Stromal Tumors of Small Intestine
title Gastrointestinal Stromal Tumors of Small Intestine
title_full Gastrointestinal Stromal Tumors of Small Intestine
title_fullStr Gastrointestinal Stromal Tumors of Small Intestine
title_full_unstemmed Gastrointestinal Stromal Tumors of Small Intestine
title_short Gastrointestinal Stromal Tumors of Small Intestine
title_sort gastrointestinal stromal tumors of small intestine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713571/
https://www.ncbi.nlm.nih.gov/pubmed/31475241
http://dx.doi.org/10.1055/s-0039-1694704
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