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Bta-miR-10b Secreted by Bovine Embryos Negatively Impacts Preimplantation Embryo Quality
In a previous study, we found miR-10b to be more abundant in a conditioned culture medium of degenerate embryos compared to that of blastocysts. Here, we show that miR-10b mimics added to the culture medium can be taken up by embryos. This uptake results in an increase in embryonic cell apoptosis an...
Autores principales: | Lin, Xiaoyuan, Pavani, Krishna Chaitanya, Smits, Katrien, Deforce, Dieter, Heindryckx, Björn, Van Soom, Ann, Peelman, Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713719/ https://www.ncbi.nlm.nih.gov/pubmed/31507632 http://dx.doi.org/10.3389/fgene.2019.00757 |
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