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Formamide catalyzed activation of carboxylic acids – versatile and cost-efficient amidation and esterification
A novel, broadly applicable method for amide C–N and ester C–O bond formation is presented based on formylpyrrolidine (FPyr) as a Lewis base catalyst. Herein, trichlorotriazine (TCT), which is the most cost-efficient reagent for OH-group activation, was employed in amounts of ≤40 mol% with respect t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713870/ https://www.ncbi.nlm.nih.gov/pubmed/31489162 http://dx.doi.org/10.1039/c9sc02126d |